National COVID Cohort CollaborativeA new effort called the National COVID Cohort Collaborative, or N3C, aims to build a centralized national data resource—the NCATS N3C Data Enclave—that the research community can use to study COVID-19 and identify potential treatments as the pandemic continues to evolve. Specifically, the N3C will enable the rapid collection and analysis of clinical, laboratory and diagnostic data from hospitals and health care plans. If successful, this approach will be applicable to other research questions and may serve as a model for addressing future public health emergencies.